Dr. Shivasharanappa Nayakvadi    Senior Scientist (Veterinary Pathology)


                                                                                    Address: S-13, Animal Science,

                                                                ICAR - CCARI,               

                                                                Old Goa 403 402

                                                                Phone: 832-2284678 Ext. 312

                                                                Fax: 0832-2285649

                                                                Email: shivasharanappa.n@icar.gov.in



Academic background:

Ph. D in Veterinary Pathology from Indian Veterinary Research Institute (Deemed University), Izatnagar, Bareilly, 2013

M. V. Sc in Veterinary Pathology from Indian Veterinary Research Institute (Deemed University), Izatnagar, Bareilly, 2008        

B. V. Sc & A.H, Veterinary College, KVAFSU, Bidar. Karnataka, 2006


Research interests and Current focus :

  • Pathology, diagnosis and epidemiology of infectious diseases of livestock in coastal region

  • Antimicrobial resistance (AMR) and its detection in livestock

Outreach and Extension

  • Involved in disease outbreak investigations and advising suitable control measures in control of infectious diseases of livestock in coastal region

  • Development of health packages and practices for control of goat diseases, popularization of goat health calendar, vaccination and health management of goats.

  • Training and consultancy service to farmers about diseases of goats and measures for their control and management and public health issues/zoonotic diseases

  • Popularization of scientific goat farming practices of konkan kanyal goats in coastal region

  • STC and SCP programs, MGMG

Memberships of professional societies

  1. Society of Toxicological Pathology (STP), VA, USA

  2. International Association for Food Protection (IAFP), Iowa, USA

  3. Association of Coastal Agricultural Scientists (ACAS)

  4. Indian Society of Sheep and Goat Production (ISSGPU)

  5. Agricultural Research Scientists Forum (ARSF)

  6. Indian Association of Veterinary Pathologists (IAVP)

  7. Veterinary Council of India (VCI), New Delhi 

  8. Karnataka Veterinary Council (KVC), Bengaluru

Awards and honours

  • Nehru-Fulbright Post-doctoral visiting scientist award to College of Veterinary Medicine, North Carolina State University, North Carolina, USA. Sept 2018 – Sept, 2019.

  • Indian National Science Academy (INSA) teacher’s fellowship-2014 for two months from June-August, 2014 on project ‘Investigation of banana flower on gene expression of antioxidant enzymes in STZ induced diabetic rats’ under Dr V Prakash, Director, JSSCMS, Mysore

  • Young Scientist award for best M.V. Sc work on “Involvement of TLR-3 and TLR-3 induced cytokines in the pathogenesis of rabies in laboratory mouse model.” At IAVP annual conference, 2008.

Research publications



  • Nayakwadi, S., Ramu, R., Kumar Sharma, A., Kumar Gupta, V., Rajukumar, K., Kumar, V., ... & Basalingappa, K. M. (2020). Toxicopathological studies on the effects of T-2 mycotoxin and their interaction in juvenile goats. PloS one, 15(3), e0229463.

  • Gururaj, K., Pawaiya, R.S., Gangwar, N.K., Mishra, A.K., Singh, D.D., Andani, D., Paul, S., Sharma, N., Shivasharanappa, N., Rahal, A. and Chaturvedi, V.K., (2019). Comparative molecular characterization and phylogenetic analysis of cerebral and non-cerebral coenurosis in Indian goats. Veterinary Parasitology: Regional Studies and Reports15, p.100266.

  • Nayakvadi, S., Alemao, C.A., Kumar, H.C., Rajkumar, R.S., Rajkumar, S., Chakurkar, E.B. and Keelara, S., (2018). Detection and Molecular characterization of sorbitol fermenting non-0157 Escherichia coli from goats.  Small Ruminant Research 161, 7–12

  • Mishra, Anil K., Desh Deepak Singh, Gururaj Kumarsen, Geetika Gupta, Nitika Sharma, Naveen Kumar, Shivasharanappa Nayakvadi, and Souvik Paul. (2017) "UspA gene based characterization of Escherichia coli strains isolated from different disease conditions in goats." Journal of Animal Research 7 (6) : 1123-1128.

  • Manjunatha, V., Singh, K. P., Saminathan, M., Singh, R., Shivasharanappa, N., Umeshappa, C. S., ... & Manjunathareddy, G. B. (2017). Inhibition of MEK-ERK1/2-MAP kinase signalling pathway reduces rabies virus induced pathologies in mouse model. Microbial Pathogenesis112, 38-49.

  • Nayakwadi Shivasharanappa, Nitika Sharma, Dinesh Kumar Sharma, Rajveer Singh Pawaiya, Beena Vamadevan, Anil Kumar Mishra and Souvik Paul (2017). Neuropathological lesions of clinical and sub clinical Coenurosis (Coenurus cerebralis) in organized goat farms in India. Acta Parasitologica, 62(2), 482–487.

  • Madhu, B. P., Singh, K. P., Saminathan, M., Singh, R., Shivasharanappa, N., Sharma, A. K., ... & Manjunatha, V. (2016). Role of nitric oxide in the regulation of immune responses during rabies virus infection in mice. Virus Disease, 27(4), 387-399.

  • Ramu, R., Shirahatti, P. S., Nayakavadi, S.,Vadivelan, R., Zameer, F., Dhananjaya, B. L., & Prasad, N. (2016).  Effect of a plant extract enriched in Stigmasterol and β-Sitosterol on glycaemic status and glucose metabolism in alloxan-induced diabetic rats. Food & Function. 14;7(9): 3999-4011.

  • Nitika Sharma, Ashok Kumar, Vinay Chaturvedi, Shivasharanappa Nayakwadi, A. K. Mishra, M. K. Singh, R. P. Pandey, Ashish Srivastava, S. Purohit, Vikrant Sudan (2016). J Parasit Dis. DOI 10.1007/s12639-016-0807-0.

  • Singh, V. K., Gupta, V. K., Shivasharanappa, N., Singh, A., Bhat, S., Kumar, R., & Gururaj, K. (2015). Differential Toll-Like Receptor and Cytokine Gene Expression Profiles in Natural Caprine Brucellosis. Journal of Pure and Applied Microbiology, June. Vol. 9(2). 1015-1023.

  • Keelara S, Malik SSV, Nayakvadi S, Das S, Barbuddhe SB (2015). Isolation and characterization of Listeria spp. from organized and migratory sheep flocks in India. Adv. Anim. Vet. Sci. 3(6): 325-331.

  • Shivasharanappa N, Gupta V K, Sharma N, Mishra A K, Singh V K, Pawaiya R V S, Gururaj K, Sharma D K, Kumar A, Paul S, Kumar N and Singh S V, (2014). Rapid Detection of Fusobacterium necrophorum as a main causative agent of foot rot in small ruminants by polymerase chain reaction assay. Adv. in Anim. and Vet. Sci. 2(5): 302 – 304.

  • Shivasharanappa N., Singh R., Singh K.P., Singh R.P., Madhu B. P (2014). Rabies virus induces expression of TLR-3 and its associated cytokines in Swiss albino mice. The Journal of Vet. Sci. Photon, 115, 384-394.

  • Gupta, V. K., Shivasharanappa, N., Kumar, V., and Kumar, A. (2014). Diagnostic evaluation of serological assays and different gene based PCR for detection of Brucella melitensis in goat. Small Ruminant Research: 117(1): 94-102.

  • Nayakwadi S, Gupta VK, Pawaiya RS, Reddy GBM, kumar A, Barbuddhe SB. (2014). Isolation and characterization of Listeria monocytogenes from goat brain. Adv. Anim. Vet. Sci. 2: 12 –15.

  • Sharma, N., Pawaiya, R., Kumar, S., & Nayakwadi, S (2014). Parasitic Encephalomyelitis in Goats due to Aberrant Infestation with Botfly Oestrous ovis Larvae. Adv. Anim. Vet. Sci. 2 (3S): 8-11.

  • Gupta VK, Nayakwadi S, Kumar A, Gururaj K, Kumar A, Pawaiya RS. (2014). Markers for the molecular diagnosis of brucellosis in animals. Adv. Anim. Vet. Sci.2 (3S): 31 – 39.

  • Gururaj K, Kirubaharan JJ, Gupta VK, Pawaiya RVS, Shivasharanappa N and Mishra AK (2014). Past and present of reverse genetics in animal virology with special reference to non–segmented negative stranded RNA viruses; a review. Adv.  Anim. Vet. Sci. 2 (3S): 40 – 48

  • Paul S, Sharma DK, Boral R, Mishra AK, Shivsharanappa N, Banerjee PS and Pawaiya RVS (2014). Cryptosporidiosis in goats; a review. Adv. Anim. Vet. Sci.2 (3S): 49 – 54.

  • Ajay Singh, Vivek Kumar Gupta, Amit Kumar, Vikas Kumar Singh and Shivasharanappa Nayakwadi (2013). 16S rRNA and Omp31 Gene Based molecular characterization of field Strains of B. melitensis from aborted foetus of goats in India. The Scientific World Journal. Volume, Article ID 160376, 7 pages,


  • Ajay, S., Gupta, V. K., Amit, K., Singh, V. K., & Shivasaranappa, N. (2018). Comparative evaluation of conventional serological tests and in-house recombinant OMP31 (rOMP31)-based ELISA for the detection of caprine brucellosis. Indian Journal of Small Ruminants24(1), 84-88.

  • Beena, V., Pawaiya, R. V. S., Singh, D. D., Gangwar, N. K., Shivasharanappa, N.,&Gururaj, K. (2016). A case of composite neoplasm of ovary in a goat having histological features of thecoma and metastatic adenocarcinoma. Indian Journal of Veterinary Pathology, 40(2), 177-180.

  • Beena, V., Pawaiya, R. V. S., Gururaj, K., Shivasharanappa, N., Singh, D. D., Gangwar, N. K., ... & Kumar, A. (2016). Pathological studies of female reproductive tract in goats. Indian Journal of Veterinary Pathology, 40(1), 27-34

  • Beena, V., Pawaiya, R. V. S., Shivasharanappa, N., Gururaj, K., Gupta, V. K., Gangwar, N. K., ... & Singh, R. (2015). Occurrence of pathological conditions in the female genitalia of goats. Indian Journal of Veterinary Pathology, 39(3), 197-201.

  • Shivasharanappa, N., Beena, V., Sharma, N., Mishra, A. K., Gururaj, K., Gupta, V. K., Pawaiya, R. V. S. (2015). Intestinal adenocarcinoma in a goat infected naturally with Mycobacterium avium subsp. paratuberculosis. Indian Journal of Veterinary Pathology, 39(2), 193-196.

  • Pawaiya, R.V.S., Shivasharanappa, N., Sharma Nitika, Mishra, A.K., Gururaj, K., Paul, S., Gupta, V.K., Kumar, A., Sharma, D.K., Kumar, N. and Singh, S.V. (2015). Patho-morphological study of a spontaneous case of mycotic pneumonia in sheep. Indian J. Vet. Pathol., 39(1): 78-80.

  • Sharma, A., Nayakwadi, S., Chandratre, G., Saini, M., Das, A., Raut, S., Swarup, D., and Somvanshi, R. (2014). Prevalence of Pathological Conditions in Zoo/Wild Animals in India: A Retrospective Study Based on Necropsy. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences, 1-10.

  • Manjunatha Reddy G B, Kumari A, Mishra A K, Shivasharanappa N, Paul S, Gupta V K and Sharma D K. (2014). Prevalence of group A rotavirus in diarrheic goat kids from organized goat farms. Indian Journal of Comparative Microbiology, Immunology & Infectious Diseases 35 (1): 9-12.

  • Ajay Singh, Vivek Kumar Gupta, Amit Kumar, Vikas Kumar Singh and Shivasharanappa Nayakwadi (2014). Omp31gene based molecular detection of B. melitensis from serum samples of goats. Indian J of Animal Science. 84 (3): 251–253, March 2014.

  • Mishra A K, Shalini, Sharma N, Kumar A and Shivasharanappa N. (2014). Prevalence of subclinical mastitis in different breeds of goats. Veterinary Practitioner 15 (1):140-141.

  • Nitika Sharma, Ashok Kumar, Ravindra Kumar, Shivasharanappa N, AK Mishra, Ashish Shrivastav and V Chaturvedi. (2013). Thiamine responsive polioencephalomalacia in a kid. Veterinary Practitioner, Vol 14(2). pp 325-326.

  • Mishra A K, Sharma N, Kumar N, Shivasharanappa N, Gururaj K, Abhishek, Paul S and Chaturvedi V, (2013). Prevalence and etiology of subclinical mastitis in Jamunapari and Barbari goats. Journal of Immunology and Immunopathology 15 (1): 142-142.

  • Nitika Sharma, Reena M, Shivasharanappa N, AK Mishra, Souvik Paul and Vinay Chaturvedi. (2013). Evaluation of Immune response of autogenous Staphylococcus aureus bacterin in mouse model mastitis. Journal of Immunology and Immunopathology, Special Issue, Vol. 15(1): Jan-June 2013. Page no 95.

  • Souvik Paul, AK Tiwari, DK Sharma, AK Mishra, Shivasharanappa N, Nitika Sharma, VK Gupta, Ashok Kumar, Vinay Chaturvedi and RVS Pawaiya. (2013). Sero-prevalence and molecular detection of Toxoplasma gondi isolates from goats in Semiarid region of India. Journal of Immunology and Immunopathology, Special Issue, Vol. 15(1): Jan-June 2013. Page no 79.

  • A.K.Sharma, N. Shivasharanappa, P.S. Banerjee, Mohini Sahini, S.S. Raut, Gauri A. Chandratre and A. Das (2012). Intestinal coccidiosis in a Nilgai calf (Boselaphus tragocamelus) Indian J. Vet. Pathol., 36(2) : 266-268.

  • Manjunatha Reddy, G.B, Shivasharanappa N, A.K. Mishra, Souvik Paul and D.K.Sharma (2012). Pathomorphological and Histopathological Lesions in Naturally Occurring Caprine Paratuberculosis. Indian J. Vet. Pathol., 36(2) : 270-272.

  • G.B. Manjunatha Reddy, A.K. Mishra, Shivasharanappa N, D. K. Gupta., D. K. Sharma, V. K. Gupta and Ashok Kumar (2012). Prevalence and Identification of Shiga toxin producing E.coli in healthy and diarrheic goats. Indian J of Comp. Microbiol. Immunol. Infect. Dis. Vol. 33 (1&2): 25-30.

  • Shivasharanappa N, K. Gururaj, D.K. Sharma, Manjunatha Reddy, G.B and V.S. Vihan. (2011). Acute Hepatic and Pneumonic Cysticercosis in Barbari Goats. Indian J of Vet. Pathol, 35(1): 80-81.

  • Shivasharanappa, N. Manjunatha Reddy, G.B., Nitika Sharma and V.K. Gupta (2011). Parasitic encephalitis caused by larvae of Oestrus ovis in Sirohi goat. Indian J. Vet. Pathol., 35(2) : 204-205.

  • Shivasharanappa, N., Singh, R. Singh K.P. and Madhu B.P (2011). NK cell and macrophage activity in experimentally induced rabies in mice. Indian J. Vet. Pathol., 35(2) : 159-161.